Change:  Genetic Code is Discovered in 1953

 

The genetic code is shared by all organisms

In 1953 Watson and Crick's Discovery of the Double Helix

 

  

The four nucleotides found in DNA differ only in their nitrogenous bases. 

 

Thymine (T) and Cytosine (C) are single-ring structures. Adenme (A) and Guanme (G) are larger, double-ring structures.  RNA has the nitrogenous base Uracil (U) instead of thymine. RNA also contains a slightly different sugar than DNA (ribose instead of deoxyribose). Other than that, RNA and DNA polynucleotides have the same chemical structure.

The discovery of ribozymes suggests that the original genetic material was RNA.

 

In 1981 it was found  that RNA  can excise 400 nucleotides in the absence of any protein.  Called ribozymes, these RNA molecules can cut out parts of their own sequences, connect some RNA molecules together, replicate others.   Self-replicating ribozymes probably first arose between 3.5 billion and 4 billion years ago.   Early life was an RNA world, with RNA molecules serving both as carriers of genetic information and as catalysts that drove the chemical reactions needed to sustain and perpetuate life. These catalytic RNA’s may have acquired the ability to synthesize protein-based enzymes, which are more efficient catalysts; with enzymes taking over more and more of the catalytic functions, DNA took on the role of information storage and transfer, eventually replacing RNA as the primary carrier of genetic

Progress on genetic enlightenment

 

Prokaryotic first life 3.5 bya

Followed by membrane housed Eukaryotic cells 1.7 bya

 

small Prokaryotic and larger Eukaryotic cells                             Microscopes enabled search

Phosphorus yellow is essential to forming DNA’s  back bone

 

Our Sun is too small a star to manufacture phosphorus

Genetic information is transferred from DNA to RNA to protein.

 

Most DNA is contained in the Nucleus   

 

Synthesis of mRNA  to cytoplasm   to synthesis of Protein

The DNA Code

 

Close-up view of transcription

 

molecule of mRNA

 

The gene is the fundamental unit of heredity ;  genes are located on chromosomes

 

non-sex cell mitosis,

 

sex cell with mitosis and meiosis

Male and female gametes (sperm and egg) differ in size

The X & Y chromosomes in humans differ in size and genetic content.

 

Genomic characteristics of humans

Universal tree of life can be constructed from 165 rRNA sequences

 

Humans

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